Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 7/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 9/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364618 | 0.87 | JAK2 (0.47) | JAK2JAK1CLK1CLK2DYRK1A | |
| SCHEMBL31364649 | 0.86 | JAK2 (0.46) | JAK2JAK1CLK1CLK2DYRK1A | |
| SCHEMBL31364613 | 0.83 | JAK2 (0.43) | JAK2JAK1CLK1CLK2DYRK1A | |
| SCHEMBL31364640 | 0.79 | AURKA (0.42) | JAK2JAK1DYRK1AEGFR | |
| SCHEMBL31364671 | 0.77 | JAK2 (0.38) | JAK2JAK1CLK1CLK2DYRK1A | |
| SCHEMBL19762902 | 0.76 | JAK2 (0.47) | JAK2JAK1CLK1CLK2DYRK1A | |
| SCHEMBL31364639 | 0.74 | AURKA (0.37) | JAK2JAK1EGFRPDE5A | |
| SCHEMBL31251463 | 0.71 | EGFR (0.45) | EGFR | |
| SCHEMBL19762905 | 0.71 | AURKA (0.48) | JAK2JAK1EGFRPDE5A | |
| SCHEMBL21195932 | 0.70 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |