Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | AURKA | O14965 | 6/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 6/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 5/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364618 | 0.89 | JAK2 (0.47) | JAK2JAK1EGFRPDE5ACLK1 | |
| SCHEMBL31364639 | 0.85 | AURKA (0.37) | JAK2JAK1EGFRAURKARPS6KB1 | |
| SCHEMBL31364650 | 0.77 | JAK2 (0.48) | JAK2JAK1EGFRPDE5ACLK1 | |
| SCHEMBL31364657 | 0.77 | AURKA (0.40) | EGFRAURKARPS6KB1AURKBDYRK1A | |
| SCHEMBL31364649 | 0.74 | JAK2 (0.46) | JAK2JAK1EGFRAURKARPS6KB1 | |
| SCHEMBL31364640 | 0.66 | AURKA (0.42) | JAK2JAK1EGFRAURKARPS6KB1 | |
| SCHEMBL19762902 | 0.65 | JAK2 (0.47) | JAK2JAK1EGFRAURKARPS6KB1 | |
| SCHEMBL31364636 | 0.65 | ALDH1A1 (0.30) | — | |
| SCHEMBL31364613 | 0.64 | JAK2 (0.43) | JAK2JAK1EGFRPDE5ACLK1 | |
| SCHEMBL31364674 | 0.64 | GRM4 (0.39) | JAK2JAK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |