Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | BCR | P11274 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825386 | 0.84 | MGLL (0.54) | BCL2L1MMP3ENPP2BACE1ALDH1A1 | |
| SCHEMBL4145743 | 0.84 | MGLL (0.54) | BCL2L1MMP3ENPP2BACE1ALDH1A1 | |
| Benzene SCHEMBL28163950 | 0.84 | ALDH1A1 (0.48) | BCL2L1ENPP2BACE1ALDH1A1HPGD | |
| SCHEMBL21933 | 0.84 | ALDH1A1 (0.48) | BCL2L1ENPP2BACE1ALDH1A1HPGD | |
| SCHEMBL29838597 | 0.84 | ALDH1A1 (0.48) | BCL2L1ENPP2BACE1ALDH1A1HPGD | |
| SCHEMBL1853561 | 0.83 | CA2 (0.44) | ENPP2ALDH1A1HPGDMEN1KMT2A | |
| Methyl Alcohol SCHEMBL28631854 | 0.82 | ALDH1A1 (0.46) | BCL2L1ENPP2BACE1ALDH1A1HPGD | |
| Water SCHEMBL29954878 | 0.82 | ALDH1A1 (0.46) | BCL2L1ENPP2BACE1ALDH1A1HPGD | |
| SCHEMBL28326904 | 0.82 | ALDH1A1 (0.46) | BCL2L1ENPP2BACE1ALDH1A1HPGD | |
| SCHEMBL29071227 | 0.81 | ESR2 (0.64) | ABL1ABCB1BCRESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029157-A | Bilobalide derivatives for the treatment of neurological diseases and cancers | 香港中文大学 | 2026-05-12 | — | — | CN | disclosed |
| US-20250144069-A1 | BILOBALIDE DERIVATIVE COMPOUNDS FOR TREATING NEUROLOGICAL DISEASES AND CANCERS | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2025-05-08 | — | — | US | disclosed |
| WO-2025031304-A1 | BILOBALIDE DERIVATIVE COMPOUNDS FOR TREATING NEUROLOGICAL DISEASES AND CANCERS | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2025-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250144069-A1 | BILOBALIDE DERIVATIVE COMPOUNDS FOR TREATING NEUROLOGICAL DISEASES AND CANCERS | BTD, BCHE, BRCA1 | ABL1 3329/4885ABCB1 48/4885BCR 3097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.