SCHEMBL3136569

SCHEMBL3136569

Cc1ccc(S(=O)(=O)[O-])cc1.FC(F)(F)c1ccc([S+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Known targets — ChEMBL curated mechanism

CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
FFAR1 O14842 1/20 0.45
CDK1 P06493 1/20 0.45
CCNB1 P14635 1/20 0.45
CCNA2 P20248 1/20 0.45
CDK2 P24941 1/20 0.45
CDK7 P50613 1/20 0.45
CCNH P51946 1/20 0.45
CCNA1 P78396 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA5A P35218 1/20 0.39
LMNA P02545 3/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KIF11 P52732 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3136043 1.00 ALDH1A1 (0.46) ALDH1A1BCHEACHEFFAR1CDK1
SCHEMBL3143572 1.00 ALDH1A1 (0.46) ALDH1A1BCHEACHEFFAR1CDK1
SCHEMBL3132913 1.00 ALDH1A1 (0.46) ALDH1A1BCHEACHEFFAR1CDK1
SCHEMBL3132680 0.92 ALDH1A1 (0.43) ALDH1A1LMNAHTTKIF11HSD11B1
SCHEMBL3139768 0.92 ALDH1A1 (0.43) ALDH1A1LMNAHTTKIF11HSD11B1
SCHEMBL503701 0.91 ALDH1A1 (0.45) ALDH1A1LMNAHTTKIF11HSD11B1
SCHEMBL5409164 0.89 FFAR1 (0.46) ALDH1A1BCHEACHEFFAR1CDK1
SCHEMBL3191563 0.89 FFAR1 (0.40) ALDH1A1BCHEACHEFFAR1CDK1
SCHEMBL5405418 0.89 FFAR1 (0.46) ALDH1A1BCHEACHEFFAR1CDK1
SCHEMBL3134860 0.88 HSD11B1 (0.42) ALDH1A1CA1CA2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed