SCHEMBL3139768

SCHEMBL3139768

FC(F)(F)c1ccc([S+](c2ccccc2)c2ccc(C(F)(F)F)cc2)cc1.O=S(=O)([O-])c1ccc(C(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
KIF11 P52732 2/20 0.43
HSD11B1 P28845 3/20 0.42
PTGES2 Q9H7Z7 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
EEF2K O00418 1/20 0.40
CYP19A1 P11511 1/20 0.39
AR P10275 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
NOD1 Q9Y239 1/20 0.38
BACE1 P56817 1/20 0.38
ACLY P53396 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132680 1.00 ALDH1A1 (0.43) ALDH1A1TSHRKIF11HSD11B1PTGES2
SCHEMBL503701 0.98 ALDH1A1 (0.45) ALDH1A1TSHRKIF11HSD11B1PTGES2
SCHEMBL3130383 0.94 RORC (0.39) ALDH1A1TSHRKIF11HSD11B1PTGES2
SCHEMBL3140028 0.94 RORC (0.39) ALDH1A1TSHRKIF11HSD11B1PTGES2
SCHEMBL3132913 0.92 ALDH1A1 (0.46) ALDH1A1TSHRKIF11HSD11B1MEN1
SCHEMBL3136569 0.92 ALDH1A1 (0.46) ALDH1A1TSHRKIF11HSD11B1MEN1
SCHEMBL3136043 0.92 ALDH1A1 (0.46) ALDH1A1TSHRKIF11HSD11B1MEN1
SCHEMBL3134860 0.92 HSD11B1 (0.42) ALDH1A1TSHRKIF11HSD11B1PTGES2
SCHEMBL3134381 0.92 CNR2 (0.41) ALDH1A1TSHRKIF11HSD11B1MAPT
SCHEMBL3139840 0.92 CNR2 (0.41) ALDH1A1TSHRKIF11HSD11B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 ALDH1A1 139/4885TSHR 1087/4885KIF11 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.