SCHEMBL3136615

SCHEMBL3136615

Fc1ccc(-c2cccc(S)c2-c2ccc(F)cc2)cc1.O=S(=O)(O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 11/20 0.39
PTGS1 P23219 4/20 0.39
DAPK1 P53355 1/20 0.35
ENPP1 P22413 1/20 0.35
SLC9A1 P19634 1/20 0.34
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
PGAM1 P18669 1/20 0.32
MAPK14 Q16539 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3139800 0.90 DAPK1 (0.37) PTGS2PTGS1DAPK1MMP2MMP9
SCHEMBL3135501 0.89 PTGS2 (0.42) PTGS2PTGS1DAPK1ENPP1MMP2
SCHEMBL3139931 0.89 PTGS2 (0.36) PTGS2PTGS1DAPK1SLC6A4SLC6A3
SCHEMBL3127195 0.88 MAPT (0.36) PGAM1MMP2MMP9
SCHEMBL3132308 0.86 HDAC4 (0.41) PTGS2PTGS1ENPP1
SCHEMBL3136649 0.86 HDAC11 (0.36) DAPK1PGAM1HSD11B1
SCHEMBL8083698 0.83 PPARG (0.34) ENPP1
Trifluoromethanesulfonic Acid SCHEMBL3130162 0.83 ENPP1 (0.42) PTGS2PTGS1ENPP1SLC9A1SLC6A4
SCHEMBL5702366 0.82 ENPP1 (0.45) PTGS2PTGS1ENPP1SLC6A4SLC6A3
SCHEMBL3137420 0.80 PTGS2 (0.44) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 PTGS2 1519/4885PTGS1 561/4885DAPK1 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.