SCHEMBL8083698

SCHEMBL8083698

CC(C)(C)Oc1ccc(-c2cccc(S)c2-c2ccc(OC(C)(C)C)cc2)cc1.O=S(=O)(O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
PPARD Q03181 1/20 0.34
ENPP1 P22413 1/20 0.30
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132308 0.87 HDAC4 (0.41) CYP2C19ENPP1
Sulfuric Acid SCHEMBL15345275 0.87 PPARG (0.37) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL8320148 0.87 PPARA (0.39) PPARGPPARACYP2C9CYP2C19PPARD
Trifluoromethanesulfonic Acid SCHEMBL216880 0.86 PPARG (0.36) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL3136649 0.85 HDAC11 (0.36)
SCHEMBL8645080 0.84 PTPN1 (0.44) CYP2C9CYP2C19
SCHEMBL3135501 0.83 PTGS2 (0.42) ENPP1
SCHEMBL3136615 0.83 PTGS2 (0.39) ENPP1
SCHEMBL246926 0.83 PPARG (0.38) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL3127195 0.82 MAPT (0.36) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6106993-A HIGHLY SENSITIVE TO ACTINIC RADIATION SUCH AS DEEP-UV, ELECTRON BEAM AND X-RAY, CAN BE DEVELOPED WITH ALKALINE AQUEOUS SOLUTION TO FORM A PATTERN, AND IS THUS SUITABLE FOR USE IN A FINE PATTERNING TECHNIQUE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-22 US disclosed
US-5824824-A AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-10-20 US disclosed