Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232450 | 0.77 | ALDH1A1 (0.50) | ACHERAPGEF4ALDH1A1KDM4ELMNA | |
| SCHEMBL30274968 | 0.77 | ALDH1A1 (0.50) | ACHERAPGEF4ALDH1A1KDM4ELMNA | |
| SCHEMBL7776329 | 0.77 | ALDH1A1 (0.50) | ACHERAPGEF4ALDH1A1KDM4ELMNA | |
| SCHEMBL5951488 | 0.76 | CA2 (0.31) | CA2LPLLIPG | |
| SCHEMBL20681138 | 0.75 | RAPGEF4 (0.36) | ACHERAPGEF4ALDH1A1KDM4ELMNA | |
| SCHEMBL31495891 | 0.75 | PTGS1 (0.33) | ACHECA1 | |
| SCHEMBL3006227 | 0.75 | ALDH1A1 (0.33) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL28951 | 0.73 | RAPGEF4 (0.59) | ACHERAPGEF4ALDH1A1KDM4ELMNA | |
| SCHEMBL1551822 | 0.73 | RAPGEF4 (0.59) | ACHERAPGEF4ALDH1A1KDM4ELMNA | |
| SCHEMBL448143 | 0.72 | CA2 (0.43) | ACHERAPGEF4ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431358-A | Pyrrolopyridines, compositions thereof and their use in medicine | 中国科学院上海药物研究所 | 2025-02-14 | — | — | CN | disclosed |