Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956488 | 1.00 | GSK3A (0.36) | GSK3AGSK3BPDGFRBKDRALDH1A1 | |
| SCHEMBL858324 | 0.84 | PDGFRB (0.44) | GSK3AGSK3BPDGFRBKDRALDH1A1 | |
| SCHEMBL30333864 | 0.82 | ALPL (0.43) | GSK3AGSK3BPDGFRBKDRALDH1A1 | |
| SCHEMBL796976 | 0.82 | ALPL (0.43) | GSK3AGSK3BPDGFRBKDRALDH1A1 | |
| SCHEMBL2065910 | 0.82 | GSK3A (0.38) | GSK3AGSK3BPDGFRBKDRMAPT | |
| SCHEMBL26833642 | 0.80 | AAK1 (0.41) | GSK3AGSK3BPDGFRBKDRALDH1A1 | |
| SCHEMBL31482797 | 0.78 | PDGFRB (0.39) | GSK3AGSK3BPDGFRBKDRALDH1A1 | |
| SCHEMBL30551407 | 0.76 | LPL (0.38) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL1181289 | 0.76 | LPL (0.38) | GSK3AGSK3BPDGFRBKDRDGAT1 | |
| SCHEMBL4550135 | 0.76 | ALDH1A1 (0.47) | ALDH1A1GPR35MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034951-A1 | PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2025024503-A1 | PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2025-01-30 | — | — | WO | disclosed |