Sugi Predict

Sugi Predict / Compounds / SCHEMBL31367585

SCHEMBL31367585

SCHEMBL31367585

Brc1ccccc1-c1cn2cc(-c3ccccc3)cc(-c3ccccc3)c2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A3 P47895 5/20 0.50
▸ ALDH1A2 O94788 4/20 0.50
▸ ALDH1A1 P00352 4/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ ADORA1 P30542 2/20 0.43
▸ ADORA2A P29274 2/20 0.42
▸ PDCD1 Q15116 2/20 0.38
▸ CD274 Q9NZQ7 2/20 0.38
▸ RAB9A P51151 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ MAPT P10636 2/20 0.37
▸ NFKB1 P19838 2/20 0.37
▸ NFKB2 Q00653 2/20 0.37
▸ RELA Q04206 2/20 0.37
▸ NPC1 O15118 2/20 0.37
▸ TP53 P04637 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ MCL1 Q07820 1/20 0.36
▸ NR1H2 P55055 1/20 0.36
▸ NR1H3 Q13133 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31367492 0.89 ALDH1A3 (0.54) ALDH1A3ALDH1A2ALDH1A1MAPK1ADORA1
SCHEMBL31367491 0.89 ALDH1A3 (0.57) ALDH1A3ALDH1A2ALDH1A1MAPK1ADORA1
SCHEMBL31367607 0.85 ALDH1A3 (0.63) ALDH1A3ALDH1A2ALDH1A1ADORA1ADORA2A
SCHEMBL31367402 0.84 ALDH1A3 (0.51) ALDH1A3ALDH1A2ALDH1A1ADORA1ADORA2A
SCHEMBL31367582 0.83 ALDH1A3 (0.50) ALDH1A3ALDH1A2ALDH1A1ADORA1ADORA2A
SCHEMBL31367576 0.83 ALDH1A3 (0.50) ALDH1A3ALDH1A2ALDH1A1ADORA1ADORA2A
SCHEMBL31367425 0.83 ALDH1A3 (0.54) ALDH1A3ALDH1A2ALDH1A1MAPK1ADORA1
SCHEMBL31367555 0.83 ALDH1A3 (0.50) ALDH1A3ALDH1A2ALDH1A1ADORA1ADORA2A
SCHEMBL31367558 0.83 ALDH1A3 (0.54) ALDH1A3ALDH1A2ALDH1A1MAPK1ADORA1
SCHEMBL31367429 0.83 ALDH1A3 (0.54) ALDH1A3ALDH1A2ALDH1A1MAPK1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735442-A1 IMIDAZO[1,2-alpha]PYRIDINE COMPOUNDS FOR USE IN TREATING CANCER AND INFLAMMATORY DISEASES AND METHODS TO PREPARE SAID COMPOUNDS Theranib Inc. (CA) 2026-05-06 — — EP claimed
US-20250011322-A1 MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A THERANIB INC. (CA) 2025-01-09 — — US claimed
EP-4735442-A1 IMIDAZO[1,2-alpha]PYRIDINE COMPOUNDS FOR USE IN TREATING CANCER AND INFLAMMATORY DISEASES AND METHODS TO PREPARE SAID COMPOUNDS Theranib Inc. (CA) 2026-05-06 — — EP disclosed
US-20250011322-A1 MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A THERANIB INC. (CA) 2025-01-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011322-A1 MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A ALDH2, ALDH3A1, ALDH1A1 ALDH1A3 8/4885ALDH1A2 4/4885ALDH1A1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.