Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22795449 | 0.78 | ALDH1A1 (0.46) | KAT2BGRM1GSK3BALDH1A1AVPR1A | |
| SCHEMBL29676576 | 0.78 | ALDH1A1 (0.46) | KAT2BGRM1GSK3BALDH1A1AVPR1A | |
| SCHEMBL22795084 | 0.78 | ALDH1A1 (0.46) | KAT2BGRM1GSK3BALDH1A1AVPR1A | |
| SCHEMBL22795445 | 0.78 | ALDH1A1 (0.46) | KAT2BGRM1GSK3BALDH1A1AVPR1A | |
| SCHEMBL21341955 | 0.77 | AVPR1A (0.54) | ALDH1A1AVPR1AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL22545823 | 0.76 | SLC6A2 (0.49) | PRMT5WDR77 | |
| SCHEMBL19844779 | 0.74 | GRM1 (0.52) | KAT2BGRM1ALDH1A1HTTKDM4E | |
| SCHEMBL13572999 | 0.74 | GRM1 (0.52) | KAT2BGRM1ALDH1A1HTTKDM4E | |
| SCHEMBL19844773 | 0.74 | GRM1 (0.52) | KAT2BGRM1ALDH1A1HTTKDM4E | |
| SCHEMBL23612701 | 0.70 | CREBBP (0.42) | PRMT5WDR77HTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739685-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | Janssen Pharmaceutica NV (BE) | 2026-05-13 | — | — | EP | claimed |
| WO-2025008061-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-09 | — | — | WO | claimed |