⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686549 | 0.80 | TEAD1 (0.35) | — | |
| SCHEMBL30686499 | 0.80 | CYP11B2 (0.36) | — | |
| SCHEMBL30686583 | 0.77 | P2RX7 (0.34) | — | |
| SCHEMBL30861575 | 0.77 | HRH1 (0.35) | — | |
| SCHEMBL30686652 | 0.66 | L3MBTL1 (0.37) | — | |
| SCHEMBL29913476 | 0.65 | PARP2 (0.35) | — | |
| SCHEMBL26863310 | 0.64 | MAPK8 (0.30) | — | |
| SCHEMBL29913595 | 0.64 | MAPK1 (0.36) | — | |
| SCHEMBL30686546 | 0.63 | HRH3 (0.36) | — | |
| SCHEMBL29913518 | 0.62 | CHRM2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320224-A1 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2025-10-16 | — | — | US | disclosed |
| CN-119384420-A | Novel PAR-2 inhibitors | 多曼治疗学公司 | 2025-01-28 | — | — | CN | disclosed |