Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TTK | P33981 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416939 | 0.79 | KDM4E (0.55) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| SCHEMBL1519993 | 0.79 | KDM4E (0.55) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| SCHEMBL29353985 | 0.79 | KDM4E (0.55) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| SCHEMBL22819499 | 0.79 | MAP2K4 (0.66) | MAP2K4KDM4EALDH1A1ALPLGAA | |
| SCHEMBL31646447 | 0.79 | KDM4E (0.55) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| SCHEMBL31642427 | 0.79 | KDM4E (0.55) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| Hydrochloric Acid SCHEMBL29702375 | 0.78 | KDM4E (0.54) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| Hydrochloric Acid SCHEMBL28694759 | 0.78 | KDM4E (0.54) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| Hydrochloric Acid SCHEMBL29604347 | 0.78 | KDM4E (0.54) | MAP2K4KDM4EALDH1A1SLC7A5GAA | |
| SCHEMBL180272 | 0.76 | SLC7A5 (0.78) | KDM4ESLC7A5ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | MAP2K4 4086/4885KDM4E 3586/4885ALDH1A1 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.