Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848256 | 0.95 | MAPT (0.57) | MAPTALDH1A1RECQLADAM17ICMT | |
| SCHEMBL25356185 | 0.81 | MAPT (0.65) | MAPTALDH1A1RECQLICMTPTGS2 | |
| SCHEMBL29552404 | 0.81 | ALDH1A1 (0.65) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL28365671 | 0.81 | CDC25A (0.56) | ALDH1A1ICMTCNR1HDAC3HDAC4 | |
| SCHEMBL1519918 | 0.81 | MAPT (0.69) | MAPTALDH1A1RECQLICMTPTGS2 | |
| SCHEMBL1519915 | 0.81 | MAPT (0.69) | MAPTALDH1A1RECQLICMTPTGS2 | |
| SCHEMBL29982985 | 0.81 | ALDH1A1 (0.65) | MAPTALDH1A1RECQLICMTPTGS2 | |
| SCHEMBL22188707 | 0.81 | ALDH1A1 (0.65) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL22188706 | 0.81 | ALDH1A1 (0.65) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL26008292 | 0.81 | MAPT (0.65) | MAPTALDH1A1RECQLICMTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | MAPT 1809/4885ALDH1A1 4472/4885RECQL 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.