Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUAK1 | O60285 | 1/20 | 1.00 |
| ▸ | NTRK1 | P04629 | 10/20 | 0.54 |
| ▸ | IGF1R | P08069 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127453 | 0.92 | NUAK1 (0.84) | NUAK1NTRK1IGF1R | |
| SCHEMBL3130134 | 0.86 | NUAK1 (0.75) | NUAK1NTRK1IGF1R | |
| SCHEMBL3127355 | 0.84 | NUAK1 (0.73) | NUAK1NTRK1IGF1R | |
| SCHEMBL3124294 | 0.81 | NUAK1 (0.68) | NUAK1NTRK1IGF1R | |
| SCHEMBL3124301 | 0.81 | NUAK1 (0.68) | NUAK1NTRK1IGF1R | |
| SCHEMBL3127072 | 0.81 | NUAK1 (0.68) | NUAK1NTRK1IGF1R | |
| SCHEMBL3127054 | 0.81 | NUAK1 (0.68) | NUAK1NTRK1IGF1R | |
| SCHEMBL4695215 | 0.76 | NUAK1 (0.61) | NUAK1NTRK1IGF1R | |
| SCHEMBL3129628 | 0.75 | NUAK1 (0.60) | NUAK1NTRK1IGF1R | |
| SCHEMBL3424837 | 0.73 | NTRK1 (0.60) | NUAK1NTRK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853602-B1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2010-07-14 | — | — | EP | disclosed |