SCHEMBL3137076

SCHEMBL3137076

CC1(C)CC(Nc2nc(N)nc(N)n2)CC(C)(C)N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
RAD52 P43351 1/20 0.41
GFER P55789 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 1/20 0.40
KCNH2 Q12809 2/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.36
MAPK14 Q16539 1/20 0.35
EHMT2 Q96KQ7 1/20 0.34
KDM1A O60341 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21894684 0.96 ALDH1A1 (0.41) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL21808060 0.88 ALDH1A1 (0.36) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL3079982 0.87 ALDH1A1 (0.47) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL21895102 0.80 ALDH1A1 (0.42) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL21895098 0.80 ALDH1A1 (0.42) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL8838292 0.79 ALDH1A1 (0.41) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL4602867 0.79 PDE4A (0.47) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL8708517 0.79 PDE4A (0.44) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL27182070 0.77 HRH4 (0.35) TSHRKCNH2GAAMAPK14POLB
SCHEMBL11343652 0.77 ALDH1A1 (0.41) ALDH1A1KMT2ALMNAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10060155-A None JP disclosed
CN-113597416-A Shaped synthetic polymer article 巴斯夫欧洲公司 2021-11-02 CN disclosed
EP-3853300-A1 USE OF A LOW MOLECULAR WEIGHT TRIAZINE BASED COMPOUND AS THERMAL / LIGHT STABILIZER IN POLYMERS Borealis AG (AT) 2021-07-28 EP disclosed
CN-111936569-A Use of ultraviolet radiation absorbing compositions as light stabilizers for shaped artificial polymeric articles 巴斯夫欧洲公司 2020-11-13 CN disclosed
WO-2020058338-A1 USE OF A LOW MOLECULAR WEIGHT TRIAZINE BASED COMPOUND AS THERMAL / LIGHT STABILIZER IN POLYMERS BOREALIS AG (AT) 2020-03-26 WO disclosed
CN-104271655-A Stabilized polyolefins with increased agrochemical and ultraviolet resistance and methods of use CYTEC TECH CORP 2015-01-07 CN disclosed
CN-101522813-B Resin composition and molded article obtained from the composition MITSU CHEMICALS INC 2013-01-30 CN disclosed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
CN-101522813-A Resin composition and molded article obtained from the composition MITSUI CHEMICALS INC (JP) 2009-09-02 CN disclosed
US-5969015-A FOR ENHANCING PERFORMANCE PROPERTIES OF LUBRICANTS, HYDRAULIC FLUIDS OR METAL PROCESSING FLUIDS WITCO VINYL ADDITIVES GMBH (DE) 1999-10-19 US disclosed
US-5804622-A STERIC HINDRANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-08 US disclosed
JP-H1060155-A MONOMERIC N-PIPERIDINYLMELAMINE AS STABILIZER FOR CHLORINATED POLYMER CIBA SPECIALTY CHEM HOLDING INC 1998-03-03 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION SEM1, WDR5, WDR1 ALDH1A1 1728/4885KMT2A 736/4885LMNA 2153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.