Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287392 | 1.00 | KMT2A (0.46) | KMT2ADPP4TSHRCYP3A4CYP2D6 | |
| SCHEMBL28696589 | 0.84 | CTSK (0.51) | MAPT | |
| SCHEMBL28598937 | 0.84 | CTSK (0.51) | MAPT | |
| SCHEMBL19797800 | 0.82 | DPP4 (0.46) | DPP4CYP1A2HSD17B10ALDH1A1CYP2C19 | |
| SCHEMBL18829154 | 0.82 | KMT2A (0.48) | KMT2ATSHRCYP3A4CYP2D6MAPK1 | |
| SCHEMBL14853205 | 0.82 | HDAC1 (0.57) | KMT2ATSHRCYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL10013666 | 0.82 | DPP4 (0.50) | DPP4CYP2D6LMNAHPGDKEAP1 | |
| SCHEMBL18269666 | 0.81 | KMT2A (0.47) | KMT2ATSHRCYP3A4CYP2D6HSD17B10 | |
| SCHEMBL18269671 | 0.81 | KMT2A (0.47) | KMT2ATSHRCYP3A4CYP2D6HSD17B10 | |
| SCHEMBL14624894 | 0.79 | CYP3A4 (0.55) | KMT2ATSHRCYP3A4CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642357-B2 | Iridium complexes | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-01-05 | — | — | US | disclosed |
| US-20090036696-A1 | IRIDIUM COMPLEXES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036696-A1 | IRIDIUM COMPLEXES | HAX1, MLX, H1-0 | KMT2A 2830/4885DPP4 2889/4885TSHR 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.