Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80210 | 0.98 | ALDH1A1 (0.46) | ALDH1A1TSHRCHRNA7ALOX5ACHE | |
| SCHEMBL21812134 | 0.89 | ALDH1A1 (0.62) | ALDH1A1TSHRCHRNA7TDP1MAPT | |
| SCHEMBL27882942 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRCHRNA7ALOX5ACHE | |
| SCHEMBL4010297 | 0.89 | CYP2C19 (0.42) | ALDH1A1TSHRCHRNA7ACHECYP2C19 | |
| SCHEMBL11697906 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRCHRNA7ALOX5ACHE | |
| SCHEMBL3675301 | 0.78 | ESR1 (0.44) | ALDH1A1ACHETDP1MAPTCYP2C19 | |
| SCHEMBL819703 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRCHRNA7ACHETDP1 | |
| SCHEMBL625329 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRACHETDP1MAPT | |
| SCHEMBL21831591 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRACHETDP1MAPT | |
| SCHEMBL9690365 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951894-B1 | Storage stable polymerizable compositions | DENTSPLY DETREY GMBH (DE) | 2010-07-14 | — | — | EP | disclosed |
| US-6998111-B2 | Storage stable polymerizable compositions | DENTAPLY DETREY GMBH (DE) | 2006-02-14 | — | — | US | disclosed |
| US-20020176826-A1 | STORAGE STABLE POLYMERIZABLE COMPOSITIONS | KLEE DR JOACHIM E (DE) | 2002-11-28 | — | — | US | disclosed |
| EP-0951894-A2 | Storage stable polymerizable compositions | DENTSPLY DETREY GmbH (DE) | 1999-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020176826-A1 | STORAGE STABLE POLYMERIZABLE COMPOSITIONS | H1-0, GPX4, H1-10 | ALDH1A1 1123/4885TSHR 4586/4885CHRNA7 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.