Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31371422 | 0.81 | BRD4 (0.43) | ATMMAPTALDH1A1BRD4 | |
| SCHEMBL15770914 | 0.81 | HSPB1 (0.51) | HSPB1TDP1L3MBTL1ATMKMT2A | |
| SCHEMBL4851442 | 0.80 | TDP1 (0.65) | HSPB1TDP1L3MBTL1ATMKMT2A | |
| SCHEMBL2443486 | 0.79 | HSPB1 (0.58) | HSPB1TDP1L3MBTL1ATMKMT2A | |
| SCHEMBL29549341 | 0.79 | HSPB1 (0.58) | HSPB1TDP1L3MBTL1ATMKMT2A | |
| SCHEMBL10960022 | 0.79 | HSPB1 (0.68) | HSPB1TDP1L3MBTL1ATMKMT2A | |
| SCHEMBL12164843 | 0.78 | PDGFRB (0.55) | TDP1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL30837492 | 0.78 | PDGFRB (0.55) | TDP1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL12108924 | 0.78 | PDGFRB (0.55) | TDP1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1365383 | 0.78 | L3MBTL1 (0.54) | HSPB1TDP1L3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056518-A1 | 5,6-DISUBSTITUTED ALKYL 1H AND 2H-INDAZOLES AS DUAL BUTYRYLCHOLINESTERASE AND p38α MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY DISEASES | UNIVERZA V LJUBLJANI (SI) | 2025-03-20 | — | — | WO | disclosed |