Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697635 | 0.75 | HSD11B1 (0.52) | EPHX2HSD11B1ANO1P2RX7 | |
| SCHEMBL16866495 | 0.74 | MEN1 (0.40) | EPHX2TLR2TLR1PLK1MLYCD | |
| SCHEMBL28978104 | 0.74 | MEN1 (0.40) | EPHX2TLR2TLR1PLK1MLYCD | |
| SCHEMBL19164207 | 0.73 | TLR2 (0.36) | EPHX2TLR2TLR1MLYCD | |
| SCHEMBL25029719 | 0.73 | TLR2 (0.37) | EPHX2TLR2TLR1PLK1MLYCD | |
| SCHEMBL16863816 | 0.73 | TLR2 (0.37) | EPHX2TLR2TLR1PLK1MLYCD | |
| SCHEMBL30271864 | 0.73 | CASP2 (0.41) | EPHX2TLR2TLR1PLK1 | |
| SCHEMBL15676126 | 0.73 | TLR2 (0.38) | EPHX2TLR2TLR1L3MBTL1PLK1 | |
| SCHEMBL15705980 | 0.73 | HSD11B1 (0.46) | EPHX2HSD11B1ANO1P2RX7L3MBTL1 | |
| SCHEMBL14742521 | 0.72 | TDP1 (0.49) | TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034789-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK DEGRADERS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-02-13 | — | — | WO | disclosed |