Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30488348 | 0.89 | HSD17B10 (0.53) | HSD17B10ESR1ADORA3CHRM1ADORA1 | |
| SCHEMBL11846346 | 0.86 | ESR1 (0.65) | HSD17B10ESR1ADORA3CHRM1ADORA1 | |
| SCHEMBL29440297 | 0.86 | HSD17B10 (0.70) | HSD17B10KDM4EMEN1KMT2AMAPT | |
| SCHEMBL21107652 | 0.86 | HSD17B10 (0.70) | HSD17B10KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29040439 | 0.82 | MAPT (0.52) | HSD17B10KDM4EMEN1KMT2ATP53 | |
| SCHEMBL22075942 | 0.82 | TSHR (0.56) | HSD17B10KDM4EMEN1KMT2ATP53 | |
| SCHEMBL30457845 | 0.82 | MAPT (0.52) | HSD17B10KDM4EMEN1KMT2ATP53 | |
| SCHEMBL30369541 | 0.82 | TSHR (0.56) | HSD17B10KDM4EMEN1KMT2ATP53 | |
| SCHEMBL11844466 | 0.82 | ESR1 (0.74) | HSD17B10ESR1ADORA3CHRM1ADORA1 | |
| SCHEMBL30457737 | 0.81 | PDK1 (0.64) | HSD17B10KDM4EMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034789-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK DEGRADERS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-02-13 | — | — | WO | disclosed |