SCHEMBL313726

SCHEMBL313726

C#Cc1ccccc1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
FFAR1 O14842 1/20 0.39
AR P10275 2/20 0.39
IDO1 P14902 2/20 0.38
SLC22A12 Q96S37 2/20 0.38
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
HSD11B1 P28845 1/20 0.35
NFKB1 P19838 1/20 0.35
KIF11 P52732 1/20 0.35
ACP3 P15309 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
HTR2C P28335 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7413846 0.83 CA1 (0.31) ALDH1A1POLBTDP1L3MBTL1AR
SCHEMBL63469 0.81 ALDH1A1 (0.52) ALDH1A1POLBTDP1L3MBTL1IDO1
SCHEMBL29441997 0.81 ALDH1A1 (0.52) ALDH1A1POLBTDP1L3MBTL1IDO1
SCHEMBL6689411 0.80 ALDH1A1 (0.40) ALDH1A1POLBTDP1L3MBTL1FFAR1
SCHEMBL30794742 0.78 AR (0.59) ARSLC22A12
SCHEMBL96903 0.78 FFAR1 (0.41) ALDH1A1POLBTDP1L3MBTL1FFAR1
SCHEMBL1861089 0.78 ALDH1A1 (0.39) ALDH1A1POLBTDP1L3MBTL1FFAR1
SCHEMBL8479886 0.78 ALDH1A1 (0.39) ALDH1A1POLBTDP1L3MBTL1FFAR1
SCHEMBL103847 0.78 AR (0.59) ARSLC22A12
SCHEMBL4299718 0.78 ALDH1A1 (0.39) ALDH1A1POLBTDP1L3MBTL1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119395917-A Preparation method of anti-mode polymer stabilized cholesteric liquid crystal intelligent window with low energy consumption and high privacy 哈尔滨工业大学 2025-02-07 CN claimed
CN-117624520-A Trifluoromethyl modified pyrenyl covalent organic framework material, and preparation method and application thereof 中国石油大学(华东) 2024-03-01 CN claimed
CN-116082390-A Preparation method of diethyl zinc catalyzed organosilane compound 北京理工大学 2023-05-09 CN claimed
CN-109851598-B Preparation method of trifluoromethyl substituted trans enol ester 江西师范大学 2022-11-29 CN claimed
CN-113548968-B Method for synthesizing (Z) -olefin by nickel-catalyzed iron-mediated alkyne fluoroalkyl and product 南京工业大学 2022-05-03 CN claimed
CN-109251192-B Preparation method of 3-position or 4-position trifluoromethyl substituted isocoumarin 江西师范大学 2022-03-04 CN claimed
CN-113548968-A Method for synthesizing (Z) -olefin by nickel-catalyzed iron-mediated alkyne fluoroalkyl and product 南京工业大学 2021-10-26 CN claimed
EP-3169674-B1 ARYL-TRIAZOLYL-PYRIDINES AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2021-01-20 EP claimed
EP-3223328-B1 ORGANIC PHOTOVOLTAIC CELL AND MANUFACTURING METHOD THEREOF KOLON INC (KR) 2020-07-29 EP claimed
CN-108329347-B Method for preparing β -chloroalkenylphosphono derivatives 苏州大学 2020-05-01 CN claimed
EP-1679720-A2 Memory device including dendrimer Samsung Electronics Co., Ltd (KR) 2006-07-12 EP claimed
US-20040159835-A1 Memory device CYPRESS SEMICONDUCTOR CORPORATION 2004-08-19 US claimed
US-20040026729-A9 Memory device COATUE CORPORATION 2004-02-12 US claimed
US-20030155602-A1 Memory device COATUE CORPORATION 2003-08-21 US claimed
EP-0922050-B1 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES ABBOTT LAB (US) 2003-07-30 EP claimed
EP-0854849-B1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF DOW CHEMICAL CO (US) 2001-10-31 EP claimed
EP-0854849-A1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF THE DOW CHEMICAL COMPANY (US) 1998-07-29 EP claimed
WO-1997010193-A1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF THE DOW CHEMICAL COMPANY (US) 1997-03-20 WO claimed
EP-0328830-B1 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds OHMEDA PHARMA PROD (US) 1994-06-01 EP claimed
EP-0050428-A1 Ethynylated aromatic compounds and process for making same Hughes Aircraft Company (US) 1982-04-28 EP claimed