Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 13/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31372600 | 0.81 | KEAP1 (0.44) | MAPTTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL23638326 | 0.78 | ALDH1A1 (0.55) | MAPTTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL23631772 | 0.78 | ALDH1A1 (0.55) | MAPTTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6353385 | 0.78 | ABCB1 (0.39) | ABCB1MAPTKDM4EALDH1A1 | |
| SCHEMBL15402070 | 0.74 | NAMPT (0.47) | — | |
| SCHEMBL2033094 | 0.73 | BRAF (0.42) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4842734 | 0.70 | ALDH1A1 (0.57) | MAPTKDM4EALDH1A1 | |
| SCHEMBL13753920 | 0.70 | HSP90AB1 (0.44) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL27467816 | 0.70 | NPC1 (0.47) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL20379477 | 0.70 | KDM4E (0.41) | ABCB1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056012-A1 | NEUTROPHIL ELASTASE INHIBITOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119638624-A | Neutrophil elastase inhibitor and application thereof | 上海壹迪生物技术有限公司 | 2025-03-18 | — | — | CN | disclosed |