Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160842 | 0.87 | KEAP1 (0.49) | KEAP1FADS1MAPK14KDM4EMEN1 | |
| SCHEMBL31372605 | 0.81 | ABCB1 (0.48) | MAPTTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL23638326 | 0.81 | ALDH1A1 (0.55) | FADS1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL23631772 | 0.81 | ALDH1A1 (0.55) | FADS1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL5063453 | 0.81 | KEAP1 (0.56) | KEAP1FADS1KDM4EALDH1A1 | |
| SCHEMBL5063446 | 0.81 | KEAP1 (0.56) | KEAP1FADS1KDM4EALDH1A1 | |
| SCHEMBL10979010 | 0.76 | KEAP1 (0.56) | KEAP1FADS1MAPTKDM4EALDH1A1 | |
| SCHEMBL31360651 | 0.75 | SLC6A3 (0.49) | MAPTTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL4333053 | 0.73 | KEAP1 (0.56) | KEAP1FADS1MAPTKDM4EALDH1A1 | |
| SCHEMBL27498122 | 0.72 | NPSR1 (0.51) | MAPK14MAPTTDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056012-A1 | NEUTROPHIL ELASTASE INHIBITOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119638624-A | Neutrophil elastase inhibitor and application thereof | 上海壹迪生物技术有限公司 | 2025-03-18 | — | — | CN | disclosed |