Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.62 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819694 | 1.00 | CES2 (0.62) | CES2NAAADGKARAD52NPSR1 | |
| SCHEMBL27658857 | 1.00 | CES2 (0.62) | CES2NAAADGKARAD52NPSR1 | |
| SCHEMBL3260402 | 0.98 | CES2 (0.59) | CES2NAAADGKARAD52NPSR1 | |
| SCHEMBL8735350 | 0.96 | CES2 (0.58) | CES2NAAADGKARAD52NPSR1 | |
| SCHEMBL17947518 | 0.96 | CES2 (0.57) | CES2NAAADGKARAD52NPSR1 | |
| SCHEMBL21070768 | 0.94 | CES2 (0.52) | CES2NAAADGKARAD52NPSR1 | |
| SCHEMBL546058 | 0.92 | CES2 (0.50) | CES2NAAADGKANPSR1KMT2A | |
| SCHEMBL8988864 | 0.92 | CES2 (0.50) | CES2NAAADGKAMEN1THRB | |
| SCHEMBL8511737 | 0.90 | NAAA (0.67) | CES2NAAADGKARAD52NPSR1 | |
| SCHEMBL6317486 | 0.90 | CES2 (0.48) | CES2NAAADGKANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345038-B1 | Non-beta-oxidizable fatty acid analogues with the effect to reduce the concentration of cholesterol and triglycerides in blood of mammals | NORSK HYDRO AS (NO) | 1993-11-03 | — | — | EP | claimed |
| EP-0345038-A2 | Non-beta-oxidizable fatty acid analogues with the effect to reduce the concentration of cholesterol and triglycerides in blood of mammals | NORSK HYDRO A/S (NO) | 1989-12-06 | — | — | EP | claimed |
| EP-0345038-B1 | Non-beta-oxidizable fatty acid analogues with the effect to reduce the concentration of cholesterol and triglycerides in blood of mammals | NORSK HYDRO AS (NO) | 1993-11-03 | — | — | EP | disclosed |
| US-5093365-A | Non-β-oxidizable fatty acid analogues with the effect to reduce the concentration of cholesterol and triglycerides in blood of mammals | NORSK HYDRO A.S. (NO) | 1992-03-03 | — | — | US | disclosed |
| EP-0345038-A2 | Non-beta-oxidizable fatty acid analogues with the effect to reduce the concentration of cholesterol and triglycerides in blood of mammals | NORSK HYDRO A/S (NO) | 1989-12-06 | — | — | EP | disclosed |