Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30675699 | 0.77 | HDAC1 (0.46) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL30675667 | 0.77 | HDAC1 (0.49) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL31374905 | 0.75 | HDAC1 (0.53) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL30675683 | 0.72 | HDAC1 (0.42) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL5507140 | 0.72 | HDAC1 (0.57) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL30675755 | 0.70 | HDAC1 (0.51) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL8853758 | 0.69 | LMNA (0.54) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL30675680 | 0.69 | PLAT (0.36) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL8853550 | 0.69 | HDAC1 (0.57) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL474617 | 0.69 | NR3C2 (0.51) | TP53KMT2AMAPTTHRBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119698413-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |