Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.58 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.58 |
| ▸ | LATS1 | O95835 | 7/20 | 0.54 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650587 | 0.84 | LATS1 (0.56) | GALR3NR2F2LATS1EGFRLATS2 | |
| SCHEMBL6837669 | 0.80 | GALR3 (0.72) | GALR3NR2F2LATS1EGFRKRAS | |
| SCHEMBL6837666 | 0.80 | GALR3 (0.72) | GALR3NR2F2LATS1EGFRKRAS | |
| SCHEMBL29650600 | 0.78 | LATS1 (0.61) | GALR3NR2F2LATS1EGFRLATS2 | |
| SCHEMBL17181108 | 0.74 | GALR3 (1.00) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL5312802 | 0.74 | GALR3 (1.00) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL31375768 | 0.73 | EGFR (0.65) | LATS1EGFRGAARAB9ADYRK1A | |
| SCHEMBL3322882 | 0.73 | EGFR (0.56) | LATS1EGFRLATS2GAA | |
| SCHEMBL22302812 | 0.72 | LATS1 (0.56) | LATS1EGFRLATS2RAB9A | |
| SCHEMBL20547986 | 0.71 | EGFR (0.62) | GALR3NR2F2LATS1EGFRLATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621222-B | 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2024-12-17 | — | — | CN | claimed |