Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | GCKR | Q14397 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390675 | 0.87 | KIF11 (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1NFKB1 | |
| SCHEMBL30767576 | 0.87 | KIF11 (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1NFKB1 | |
| SCHEMBL30767660 | 0.84 | KDM1A (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1NFKB1 | |
| SCHEMBL30767444 | 0.84 | KIF11 (0.40) | RAB9ANPC1SMN1; SMN2L3MBTL1NFKB1 | |
| SCHEMBL31375576 | 0.80 | KDM1A (0.44) | KIF11CYP11B1CYP11B2KDM1AMAOB | |
| SCHEMBL16446207 | 0.77 | ALDH1A1 (0.40) | MAOB | |
| SCHEMBL31374887 | 0.75 | CHRM5 (0.44) | RAB9ANPC1L3MBTL1KCNH2MAPT | |
| SCHEMBL32670328 | 0.75 | CYP11B1 (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1NFKB1 | |
| SCHEMBL507838 | 0.75 | CYP11B1 (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1NFKB1 | |
| SCHEMBL8239616 | 0.74 | KIF11 (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |