Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | SDHB | P21912 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FUBP1 | Q96AE4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375574 | 0.82 | SMN1; SMN2 (0.39) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL26375525 | 0.79 | KDM1A (0.46) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL26375527 | 0.74 | PTPN1 (0.40) | ARALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8989162 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL22337526 | 0.73 | KMT2A (0.44) | CYP11B1CYP11B2SMN1; SMN2SDHBKDM4E | |
| SCHEMBL26375530 | 0.71 | KDM1A (0.40) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13865687 | 0.71 | RAB9A (0.39) | CYP11B1CYP11B2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28881729 | 0.70 | TRPV3 (0.48) | CYP11B1CYP11B2ALDH1A1MAPTPOLB | |
| SCHEMBL26375523 | 0.70 | TRPV3 (0.47) | POLBGAA | |
| SCHEMBL21139679 | 0.70 | KDM4E (0.42) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |