SCHEMBL8989162

SCHEMBL8989162

Cc1ccc(-c2ccc(C)c(C)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.56
ENPP3 O14638 1/20 0.44
ENPP1 P22413 1/20 0.44
KMT2A Q03164 7/20 0.43
MEN1 O00255 6/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
ALDH1A1 P00352 6/20 0.42
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
KDM4E B2RXH2 5/20 0.42
LMNA P02545 3/20 0.42
MITF O75030 2/20 0.42
KDM5A P29375 1/20 0.42
KDM5C P41229 1/20 0.42
PAX8 Q06710 1/20 0.42
MAPT P10636 4/20 0.42
TP53 P04637 3/20 0.42
HPGD P15428 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13299549 0.82 ALDH1A1 (0.58) SMN1; SMN2KMT2AMEN1NOS3NOS1
Ammonia Solution, Strong SCHEMBL28686928 0.80 ALDH1A1 (0.56) SMN1; SMN2KMT2AMEN1NOS3NOS1
SCHEMBL24523646 0.80 NPC1 (0.49) SMN1; SMN2KMT2AMEN1NOS3NOS1
SCHEMBL24525893 0.80 SMN1; SMN2 (0.46) SMN1; SMN2ENPP3ENPP1KMT2AMEN1
SCHEMBL3071714 0.80 NOS3 (0.55) SMN1; SMN2NOS3NOS1NOS2ALDH1A1
SCHEMBL8989104 0.78 SMN1; SMN2 (0.45) SMN1; SMN2ENPP3ENPP1KMT2AMEN1
SCHEMBL18136462 0.77 PTGS2 (0.44)
SCHEMBL14184288 0.76 SMN1; SMN2 (0.50) SMN1; SMN2ENPP3ENPP1KMT2AMEN1
SCHEMBL13299577 0.75 KMO (0.47) SMN1; SMN2ENPP3ALDH1A1NPC1RAB9A
SCHEMBL25455888 0.75 XDH (0.46) SMN1; SMN2KMT2AMEN1NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230348508-A1 METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT BEIJING BAYI SPACE LIQUID CRYSTAL TECHNOLOGY CO. LTD. (CN) 2023-11-02 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-11785839-B2 Organic light-emitting materials containing cyano-substituted ligand Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-10 US disclosed
US-20220194974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-06-23 US disclosed
US-20220165968-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-05-26 US disclosed
US-20220162246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-26 US disclosed
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 US disclosed
US-11233203-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-25 US disclosed
US-20210280802-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2021-09-09 US disclosed
US-20200251666-A1 ORGANIC LIGHT-EMITTING MATERIALS CONTAINING CYANO-SUBSTITUTED LIGAND Beijing Summer Sprout Technology Co., Ltd. (CN) 2020-08-06 US disclosed
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-11 US disclosed
US-5545645-A Heterocyclic derivatives in the treatment of ischaemia and related diseases SYNTEX PHARMACEUTICALS, LIMITED (GB) 1996-08-13 US disclosed
US-5428037-A Piperazine derivatives; calcium and sodium channel antagonists SYNTEX PHARMACEUTICALS, LTD. (GB) 1995-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR SMN1; SMN2 3281/4885ENPP3 967/4885ENPP1 2249/4885
US-20200251666-A1 ORGANIC LIGHT-EMITTING MATERIALS CONTAINING CYANO-SUBSTITUTED LIGAND L1CAM, CYBA, ICOSLG SMN1; SMN2 3541/4885ENPP3 1995/4885ENPP1 2187/4885
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LBR SMN1; SMN2 1928/4885ENPP3 1693/4885ENPP1 1982/4885
US-20220194974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC SMN1; SMN2 2763/4885ENPP3 1262/4885ENPP1 1384/4885
US-11785839-B2 Organic light-emitting materials containing cyano-substituted ligand L1CAM, CYBA, ICOSLG SMN1; SMN2 3541/4885ENPP3 1995/4885ENPP1 2187/4885
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NR1H2 SMN1; SMN2 3696/4885ENPP3 4287/4885ENPP1 4238/4885
US-11233203-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM SMN1; SMN2 4216/4885ENPP3 293/4885ENPP1 609/4885
US-20220162246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 SMN1; SMN2 3174/4885ENPP3 2329/4885ENPP1 1717/4885
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG SMN1; SMN2 2990/4885ENPP3 1066/4885ENPP1 462/4885
US-20220165968-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, PIEZO1, L1CAM SMN1; SMN2 3245/4885ENPP3 3145/4885ENPP1 2199/4885
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM SMN1; SMN2 2241/4885ENPP3 3966/4885ENPP1 3950/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR SMN1; SMN2 3773/4885ENPP3 3890/4885ENPP1 4033/4885
US-20210280802-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE MLX, L1CAM, MCOLN1 SMN1; SMN2 3561/4885ENPP3 2814/4885ENPP1 2577/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 SMN1; SMN2 3772/4885ENPP3 2817/4885ENPP1 3990/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 SMN1; SMN2 3270/4885ENPP3 2462/4885ENPP1 3204/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 SMN1; SMN2 3599/4885ENPP3 2464/4885ENPP1 2903/4885
US-20230348508-A1 METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT TRPM5, TRPM6, TRPM2 SMN1; SMN2 2076/4885ENPP3 123/4885ENPP1 137/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 SMN1; SMN2 2191/4885ENPP3 1236/4885ENPP1 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.