Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375972 | 1.00 | CTSL (0.46) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL29132687 | 0.76 | CTSL (0.50) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL582674 | 0.76 | CTSL (0.50) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL425330 | 0.76 | CTSL (0.50) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL25303971 | 0.75 | CTSL (0.46) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL2647482 | 0.75 | CTSL (0.53) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL6469380 | 0.74 | OPRM1 (0.59) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL29378300 | 0.73 | SLC6A4 (0.44) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL19023261 | 0.73 | SLC6A4 (0.44) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL15797812 | 0.73 | OPRM1 (0.54) | CTSLCTSBCTSKOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |