Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 5/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582674 | 0.88 | CTSL (0.50) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL23050100 | 0.88 | CTSL (0.44) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL425330 | 0.80 | CTSL (0.50) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL6469380 | 0.79 | OPRM1 (0.59) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL23258242 | 0.78 | CARM1 (0.46) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL29699608 | 0.78 | TSHR (0.44) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL16016112 | 0.77 | OPRM1 (0.50) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL29260378 | 0.76 | CTSL (0.50) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL31375974 | 0.76 | CTSL (0.46) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL25303971 | 0.76 | CTSL (0.46) | CTSLCTSBCTSKOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203202-A | Quinoxaline derivative and use thereof | 黑钻治疗公司 | 2023-12-08 | — | — | CN | disclosed |