Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261063 | 0.79 | — | — | |
| SCHEMBL25404157 | 0.78 | PRMT5 (0.37) | EPAS1 | |
| SCHEMBL31353077 | 0.77 | TRPV4 (0.42) | TP53MAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL24495455 | 0.74 | RAB9A (0.42) | LMNANPSR1MAPTKMT2AKDM4E | |
| SCHEMBL27807167 | 0.70 | NPC1 (0.39) | LMNANPSR1MAPTKMT2AKDM4E | |
| SCHEMBL4401613 | 0.70 | MAPT (0.37) | LMNATP53MAPTKMT2AKDM4E | |
| SCHEMBL29472371 | 0.70 | MAPT (0.49) | LMNAMAPTKMT2AKDM4ERAB9A | |
| SCHEMBL4406875 | 0.70 | KDM4E (0.42) | LMNAMAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL5238964 | 0.70 | KDM4E (0.42) | LMNAMAPTKMT2AKDM4ERAB9A | |
| SCHEMBL8762033 | 0.69 | NPSR1 (0.41) | LMNANPSR1TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |