Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29176715 | 0.81 | TRPV4 (0.39) | TRPV4TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL24253799 | 0.78 | TRPV4 (0.52) | TRPV4 | |
| SCHEMBL31376014 | 0.77 | LMNA (0.36) | EPAS1ALDH1A1TP53CYP3A4MAPT | |
| SCHEMBL23087497 | 0.76 | TRPV4 (0.42) | TRPV4TAS1R3TAS1R1TAS1R2KHK | |
| SCHEMBL7629039 | 0.75 | TRPV4 (0.45) | TRPV4TAS1R3TAS1R1TAS1R2KHK | |
| SCHEMBL1806589 | 0.73 | TRPV4 (0.43) | TRPV4TAS1R3TAS1R1TAS1R2KHK | |
| SCHEMBL25242758 | 0.73 | TRPV4 (0.34) | TRPV4TAS1R3TAS1R1TAS1R2EPAS1 | |
| SCHEMBL9693854 | 0.73 | TRPV4 (0.41) | TRPV4TAS1R3TAS1R1TAS1R2KHK | |
| SCHEMBL31388135 | 0.73 | ALDH1A1 (0.49) | MEN1ALDH1A1TP53MAPTHPGD | |
| SCHEMBL3842293 | 0.72 | TRPV4 (0.46) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301101-A | Methylpyrazole compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119143752-A | Aminoquinoline derivative, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |