Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834398 | 0.89 | METAP2 (0.34) | SLC18A3CXCR4HSD17B10ALDH1A1METAP2 | |
| SCHEMBL25834397 | 0.89 | METAP2 (0.34) | SLC18A3CXCR4HSD17B10ALDH1A1METAP2 | |
| SCHEMBL31376570 | 0.89 | METAP2 (0.34) | SLC18A3CXCR4HSD17B10ALDH1A1METAP2 | |
| SCHEMBL31376581 | 0.84 | HSD17B10 (0.31) | HSD17B10METAP2 | |
| SCHEMBL25834386 | 0.83 | METAP2 (0.44) | TDP1HSD17B10METAP2RAB9AMCHR1 | |
| SCHEMBL25834475 | 0.83 | METAP2 (0.44) | TDP1HSD17B10METAP2RAB9AMCHR1 | |
| SCHEMBL25837289 | 0.83 | METAP2 (0.44) | TDP1HSD17B10METAP2RAB9AMCHR1 | |
| SCHEMBL31376551 | 0.81 | PARP1 (0.34) | SLC18A3CXCR4 | |
| SCHEMBL5556750 | 0.79 | MAPT (0.49) | TSHRDRD2HTR2ASLC18A3MAPT | |
| SCHEMBL18991158 | 0.79 | MAPT (0.49) | TSHRDRD2HTR2ASLC18A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250065315-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) | 2025-02-27 | — | — | US | disclosed |
| EP-4491270-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | The University of Hong Kong (HK) | 2025-01-15 | — | — | EP | disclosed |
| CN-119306769-A | Iron complexes for enantioselective cis dihydroxylation of olefins | 香港大学 | 2025-01-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250065315-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | SQLE, NFE2L2, FECH | TSHR 2082/4885SLC6A2 798/4885SLC6A4 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.