SCHEMBL5556750

SCHEMBL5556750

CN(Cc1ccccn1)C1CCCCC1N(C)Cc1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LIN28A Q9H9Z2 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
SLC18A3 Q16572 1/20 0.46
TSHR P16473 2/20 0.45
HRH3 Q9Y5N1 2/20 0.42
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
KCNA5 P22460 1/20 0.41
PSEN1 P49768 1/20 0.41
PSEN2 P49810 1/20 0.41
APH1B Q8WW43 1/20 0.41
NCSTN Q92542 1/20 0.41
APH1A Q96BI3 1/20 0.41
PSENEN Q9NZ42 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18991158 1.00 MAPT (0.49) MAPTSMN1; SMN2LIN28ATDP1SLC18A3
SCHEMBL26620842 0.95 MAPT (0.45) MAPTSMN1; SMN2LIN28ATDP1SLC18A3
SCHEMBL27010666 0.90 SMN1; SMN2 (0.41) MAPTSMN1; SMN2LIN28ATDP1SLC18A3
SCHEMBL26620841 0.87 TSHR (0.42) MAPTSMN1; SMN2LIN28ATDP1SLC18A3
SCHEMBL17376555 0.87 TSHR (0.51) MAPTSMN1; SMN2LIN28ATDP1TSHR
SCHEMBL3122498 0.85 TSHR (0.50) MAPTSMN1; SMN2LIN28ATDP1TSHR
SCHEMBL27010670 0.85 TSHR (0.40) MAPTSMN1; SMN2LIN28ATDP1SLC18A3
SCHEMBL17888208 0.83 TDP1 (0.52) MAPTSMN1; SMN2LIN28ATDP1TSHR
SCHEMBL7194917 0.79 TDP1 (0.52) MAPTSMN1; SMN2LIN28ATDP1TSHR
SCHEMBL31376557 0.79 TSHR (0.35) MAPTSMN1; SMN2LIN28ATDP1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3307941-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP claimed
EP-3307940-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP claimed
US-10882745-B2 Oxidative method CATEXEL TECHNOLOGIES LIMITED (GB) 2021-01-05 US claimed
US-10815616-B2 Oxidative method CATEXEL TECHNOLOGIES LIMITED (GB) 2020-10-27 US claimed
US-20180186634-A1 OXIDATIVE METHOD CATEXEL B.V. (NL) 2018-07-05 US claimed
EP-3307940-A1 OXIDATIVE METHOD Catexel Technologies Limited (GB) 2018-04-18 EP claimed
US-20180094384-A1 OXIDATIVE METHOD CATEXEL B.V. (NL) 2018-04-05 US claimed
WO-2016198890-A1 OXIDATIVE METHOD CHEMSENTI LIMITED (GB) 2016-12-15 WO claimed
EP-3307940-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP disclosed
EP-3307941-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP disclosed
US-10882745-B2 Oxidative method CATEXEL TECHNOLOGIES LIMITED (GB) 2021-01-05 US disclosed
US-10815616-B2 Oxidative method CATEXEL TECHNOLOGIES LIMITED (GB) 2020-10-27 US disclosed
US-20180186634-A1 OXIDATIVE METHOD CATEXEL B.V. (NL) 2018-07-05 US disclosed
EP-3307940-A1 OXIDATIVE METHOD Catexel Technologies Limited (GB) 2018-04-18 EP disclosed
US-20020013246-A1 Composition and method for bleaching laundry fabrics UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-31 US disclosed
US-20020013247-A1 Composition and method for bleaching a substrate UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-31 US disclosed
US-20020010121-A1 Bleaching and dye transfer inhibiting composition and method for laundry fabrics UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-24 US disclosed
US-6340661-B1 FOR BLEACHING FABRIC STAINS WITHOUT UNACCEPTABLE TRANSFER OF DYES BETWEEN FABRICS UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-22 US disclosed
US-6302921-B1 NON PEROXY BLEACH UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-10-16 US disclosed
WO-2000060043-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2000-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815616-B2 Oxidative method CAT, LPO, MPO MAPT 2450/4885SMN1; SMN2 1826/4885LIN28A 4225/4885
US-10882745-B2 Oxidative method CAT, LPO, GPX4 MAPT 3440/4885SMN1; SMN2 4606/4885LIN28A 4737/4885
US-20180094384-A1 OXIDATIVE METHOD CAT, LPO, MPO MAPT 2450/4885SMN1; SMN2 1826/4885LIN28A 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.