SCHEMBL31377005

SCHEMBL31377005

BrCc1ccc(Cc2ccc(-c3ccc(Cc4ccc(CBr)cc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TSHR P16473 3/20 0.48
TRPA1 O75762 1/20 0.48
CYP17A1 P05093 7/20 0.43
CYP11B1 P15538 6/20 0.43
CYP11B2 P19099 6/20 0.43
CYP3A4 P08684 5/20 0.43
CYP19A1 P11511 4/20 0.43
HRH3 Q9Y5N1 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CALM1 P0DP23 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609757 0.91 TSHR (0.56) ALDH1A1TSHRTRPA1HRH3ESR1
SCHEMBL679626 0.91 TSHR (0.56) ALDH1A1TSHRTRPA1HRH3ESR1
SCHEMBL5885289 0.91 ALDH1A1 (0.56) ALDH1A1TSHRTRPA1CYP3A4TDP1
Methane SCHEMBL11480910 0.88 TSHR (0.53) ALDH1A1TSHRTRPA1HRH3ESR1
Water SCHEMBL11481683 0.88 TSHR (0.53) ALDH1A1TSHRTRPA1HRH3ESR1
SCHEMBL10049247 0.82 TRPA1 (0.48) ALDH1A1TSHRTRPA1CYP17A1CYP11B1
SCHEMBL131361 0.80 ALDH1A1 (0.67) ALDH1A1TSHRTRPA1CYP3A4HRH3
SCHEMBL712948 0.80 TRPA1 (0.78) ALDH1A1TSHRTRPA1TDP1CA12
SCHEMBL1374017 0.80 ALDH1A1 (0.68) ALDH1A1TSHRTRPA1CYP3A4TDP1
SCHEMBL3362246 0.80 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1HRH3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462762-A Chiral ring papain BinapoBox.4PF6Preparation method and application thereof 黑龙江大学 2025-02-18 CN claimed
CN-119462762-A Chiral ring papain BinapoBox.4PF6Preparation method and application thereof 黑龙江大学 2025-02-18 CN disclosed