SCHEMBL31377102

SCHEMBL31377102

C#Cc1ccc(C[C@@H]2[C@H](OC(C)=O)[C@@H](O)CN2C(=O)OC(C)(C)C)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ SLC2A1 P11166 1/20 0.35
▸ RORC P51449 2/20 0.34
▸ NR1H2 P55055 2/20 0.34
▸ NR1H3 Q13133 2/20 0.34
▸ AR P10275 1/20 0.33
▸ GPR119 Q8TDV5 1/20 0.32
▸ GABRG2 P18507 2/20 0.32
▸ GABRB3 P28472 2/20 0.32
▸ GABRA5 P31644 2/20 0.32
▸ GABRA6 Q16445 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31377384 0.90 AR (0.43) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377105 0.87 CYP2D6 (0.38) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421262 0.87 NR1H2 (0.33) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377193 0.86 VEGFA (0.38) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377217 0.86 RORC (0.38) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377169 0.86 GABRA5 (0.36) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377211 0.86 NR1H2 (0.45) NR1H2NR1H3TACR1STS
SCHEMBL31377178 0.86 NR1H2 (0.45) NR1H2NR1H3TACR1STS
SCHEMBL31377297 0.85 SMN1; SMN2 (0.51) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377351 0.84 NR1H2 (0.40) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CYP2D6 2734/4885SMN1; SMN2 1694/4885LMNA 2869/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CYP2D6 2401/4885SMN1; SMN2 1576/4885LMNA 3037/4885
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 CYP2D6 3364/4885SMN1; SMN2 958/4885LMNA 2918/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS CYP2D6 2744/4885SMN1; SMN2 1323/4885LMNA 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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