SCHEMBL31377217

SCHEMBL31377217

CC(=O)O[C@H]1[C@@H](Cc2ccc(Br)cc2)N(C(=O)OC(C)(C)C)C[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 4/20 0.38
▸ CYP2D6 P10635 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ LMNA P02545 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ HIF1A Q16665 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SLC2A1 P11166 1/20 0.37
▸ NR1H2 P55055 3/20 0.36
▸ NR1H3 Q13133 3/20 0.36
▸ KCNK3 O14649 2/20 0.34
▸ KCNK9 Q9NPC2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31377105 0.90 CYP2D6 (0.38) RORCCYP2D6SMN1; SMN2LMNAMAPK1
SCHEMBL31377193 0.89 VEGFA (0.38) RORCCYP2D6SMN1; SMN2LMNAMAPK1
SCHEMBL31377211 0.89 NR1H2 (0.45) NR1H2NR1H3
SCHEMBL31377178 0.89 NR1H2 (0.45) NR1H2NR1H3
SCHEMBL31377297 0.88 SMN1; SMN2 (0.51) RORCCYP2D6SMN1; SMN2LMNAMAPK1
SCHEMBL31377351 0.87 NR1H2 (0.40) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377384 0.86 AR (0.43) RORCCYP2D6SMN1; SMN2LMNAMAPK1
SCHEMBL31377102 0.86 CYP2D6 (0.35) RORCCYP2D6SMN1; SMN2LMNAMAPK1
SCHEMBL31377299 0.85 ABHD6 (0.41) RORCCYP2D6SMN1; SMN2LMNAMAPK1
SCHEMBL31421470 0.85 GPR119 (0.40) RORCCYP2D6SMN1; SMN2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS RORC 2401/4885CYP2D6 2734/4885SMN1; SMN2 1694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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