Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965925 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTPPARGRAB9ANCOA2 | |
| SCHEMBL28895268 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTPPARGRAB9ANCOA2 | |
| SCHEMBL29965297 | 0.74 | PARP1 (0.59) | TP53LMNAALDH1A1MAPTPPARG | |
| SCHEMBL9094909 | 0.74 | GRIA1 (0.51) | TP53ALDH1A1RAB9ASMN1; SMN2PDE5A | |
| SCHEMBL3786255 | 0.74 | PARP1 (0.59) | TP53LMNAALDH1A1MAPTPPARG | |
| SCHEMBL31377505 | 0.74 | MAPT (0.43) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31377488 | 0.74 | MAPT (0.43) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31377439 | 0.74 | ATM (0.43) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31377504 | 0.72 | SIRT2 (0.42) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30237524 | 0.70 | ALDH1A1 (0.55) | LMNAALDH1A1MAPTSMN1; SMN2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219640-A | Nitrogen-containing ternary condensed ring derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |