SCHEMBL31377421

SCHEMBL31377421

CN(C)S(=O)(=O)c1cc(C(=O)Cl)ccc1F

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.41
LMNA P02545 8/20 0.40
TP53 P04637 3/20 0.40
KDM4E B2RXH2 1/20 0.40
KMT2A Q03164 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 3/20 0.40
HTT P42858 2/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PTK2B Q14289 2/20 0.39
KCNJ6 P48051 2/20 0.39
KCNJ5 P48544 2/20 0.39
KCNJ3 P48549 2/20 0.39
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11187869 0.85 PTK2B (0.54) MAPTLMNATP53KDM4EKMT2A
SCHEMBL11596069 0.82 SMN1; SMN2 (0.54) LMNAKMT2ASMN1; SMN2MEN1MAPK1
SCHEMBL9900899 0.81 PTK2B (0.42) MAPTTP53SMN1; SMN2PTK2B
SCHEMBL940704 0.80 PTK2B (0.43) MAPTLMNATP53KDM4ESMN1; SMN2
SCHEMBL18948550 0.79 PTK2B (0.40) MAPTLMNATP53KDM4EKMT2A
SCHEMBL11169516 0.78 PTK2B (0.42) MAPTTP53SMN1; SMN2PTK2BCYP2C19
SCHEMBL15847936 0.76 LMNA (0.67) MAPTLMNATP53KDM4EKMT2A
SCHEMBL31429893 0.73 TSHR (0.41) MAPTLMNATP53KMT2ASMN1; SMN2
SCHEMBL22968036 0.72 GSTO1 (0.48) MAPTLMNAKMT2AMEN1KCNJ6
SCHEMBL2517845 0.72 MAPT (0.55) MAPTLMNAKMT2ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS MAPT 2060/4885LMNA 2869/4885TP53 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.