SCHEMBL31377474

SCHEMBL31377474

CCOC(=O)c1cc(C(C)(C)C)n(-c2ccccc2)n1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.68
KMT2A Q03164 4/20 0.62
GAA P10253 1/20 0.62
CNR1 P21554 1/20 0.59
CNR2 P34972 1/20 0.59
MAPT P10636 4/20 0.59
TP53 P04637 3/20 0.57
TDP1 Q9NUW8 2/20 0.56
POLB P06746 1/20 0.56
MEN1 O00255 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
THRB P10828 1/20 0.55
LMNA P02545 1/20 0.55
PDE4D Q08499 1/20 0.53
CA9 Q16790 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979716 0.90 CNR1 (0.61) ALDH1A1KMT2AGAACNR1CNR2
SCHEMBL28820555 0.87 CNR1 (0.61) ALDH1A1KMT2AGAACNR1CNR2
SCHEMBL4501553 0.87 ALDH1A1 (0.51) ALDH1A1KMT2AGAACNR1CNR2
SCHEMBL1107579 0.84 CA9 (0.53) ALDH1A1KMT2AGAACNR1CNR2
SCHEMBL7268 0.83 KMT2A (0.68) ALDH1A1KMT2AGAAMAPTTP53
SCHEMBL3299372 0.83 KMT2A (0.68) ALDH1A1KMT2AGAAMAPTTP53
SCHEMBL28625965 0.82 KMT2A (0.67) ALDH1A1KMT2AGAAMAPTTP53
SCHEMBL4083414 0.82 ALDH1A1 (1.00) ALDH1A1KMT2ACNR1CNR2MEN1
SCHEMBL22896893 0.81 KMT2A (0.65) ALDH1A1KMT2AGAAMAPTTP53
SCHEMBL2835335 0.81 KMT2A (0.65) ALDH1A1KMT2AGAAMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219559-A Cis-enamide-pyrazole derivative and application thereof in anti-inflammatory drugs 广东省科学院动物研究所 2024-12-31 CN disclosed