Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120846 | 0.81 | MAPK8 (0.54) | MAPK8TYMSADORA2AHTR3EHTR3B | |
| SCHEMBL30578099 | 0.81 | MAPK8 (0.54) | MAPK8TYMSADORA2AHTR3EHTR3B | |
| SCHEMBL3496046 | 0.78 | HTR3E (0.40) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8279650 | 0.76 | HTR3E (0.38) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31377508 | 0.75 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL124061 | 0.75 | KDM4E (0.51) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL18584266 | 0.75 | RAD51 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3498276 | 0.75 | KDM4E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8118650 | 0.74 | GRIN2D (0.49) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11493554 | 0.72 | MAPK8 (0.52) | MAPK8HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219640-A | Nitrogen-containing ternary condensed ring derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |