Sugi Predict

Sugi Predict / Compounds / SCHEMBL313779

SCHEMBL313779

SCHEMBL313779

COC(=O)C(CO)NC(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ CTSK P43235 9/20 0.46
▸ CTSS P25774 5/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA7 P43166 1/20 0.46
▸ CTSL P07711 2/20 0.44
▸ CTSB P07858 1/20 0.44
▸ NFKB1 P19838 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43
▸ RELA Q04206 1/20 0.43
▸ KLK5 Q9Y337 1/20 0.43
▸ CA12 O43570 1/20 0.42
▸ CA14 Q9ULX7 1/20 0.42
▸ CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313780 1.00 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL3617926 1.00 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL11173165 0.91 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL1846647 0.91 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL2531297 0.91 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL15214454 0.87 KLK5 (0.41) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL800751 0.87 KMT2A (0.44) CYP2C9CYP2C19CTSKCTSSCA1
SCHEMBL12555978 0.87 KMT2A (0.44) CYP2C9CYP2C19CTSKCTSSCA1
SCHEMBL2555252 0.87 KMT2A (0.44) CYP2C9CYP2C19CTSKCTSSCA1
SCHEMBL18220550 0.87 KMT2A (0.44) CYP2C9CYP2C19CTSKCTSSCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909067-B Organic total synthesis method of D-penicillamine 浙江凯普化工有限公司 2022-03-15 — — CN claimed
CN-111909067-A Organic total synthesis method of D-penicillamine 浙江凯普化工有限公司 2020-11-10 — — CN claimed
CN-108047268-B 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application 中国科学技术大学 2020-05-01 — — CN claimed
CN-105209439-A Process for manufacture of gadofosveset trisodium monohydrate LANTHEUS MEDICAL IMAGING INC 2015-12-30 — — CN claimed
CN-103601706-B Method for synthesizing natural product Jaspine B isomer UNIV JIANGXI NORMAL SCI & TECH 2015-07-01 — — CN claimed
CN-103601706-A Method for synthesizing natural product Jaspine B isomer UNIV JIANGXI NORMAL SCI & TECH 2014-02-26 — — CN claimed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 — — US disclosed
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-11-06 — — US disclosed
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-10-16 — — US disclosed
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 — — US disclosed
US-12427124-B1 Phenylalanine-based LAT1 inhibitors and uses thereof Maxymune Therapeutics, Inc. (US) 2025-09-30 — — US disclosed
US-12377100-B2 Toll like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2025-08-05 — — US disclosed
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 — — EP disclosed
EP-1008587-A1 Serine carbonates Givaudan Roure (International) S.A. (CH) 2000-06-14 — — EP disclosed
US-6025444-A HYALURONIC ACID POLYSACCHARIDE DERIVATIVE; PHOTODIMERIZABLE, CROSSLINKABLE SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 2000-02-15 — — US disclosed
EP-0713859-A2 Cinnamic acid derivatives, photocrosslinkable cinnamic acid-polymer derivative and crosslinked cinnamic acid polymer derivatives SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1996-05-29 — — EP disclosed
EP-0278621-B1 SUBSTITUTED AMINE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1991-06-12 — — EP disclosed
US-4987130-A ANTIARRHYTHMIA AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-01-22 — — US disclosed
EP-0278621-A1 Substituted amine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1988-08-17 — — EP disclosed
US-4401658-A VACCINE ADJUVANTS, IMMUNOSTIMULANTS RHONE-POULENC SANTE (FR) 1983-08-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 CYP1A2 1381/4885CYP2C9 921/4885CYP2C19 2008/4885
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 CYP1A2 3594/4885CYP2C9 3645/4885CYP2C19 3812/4885
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 CYP1A2 2169/4885CYP2C9 2725/4885CYP2C19 2048/4885
US-12427124-B1 Phenylalanine-based LAT1 inhibitors and uses thereof SLC43A1, SLC7A1, SLC1A5 CYP1A2 3594/4885CYP2C9 3645/4885CYP2C19 3812/4885
US-12377100-B2 Toll like receptor modulator compounds TLR8, TLR3, TLR6 CYP1A2 4675/4885CYP2C9 4746/4885CYP2C19 4677/4885
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 CYP1A2 3594/4885CYP2C9 3645/4885CYP2C19 3812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.