Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545928 | 0.88 | KDM4E (0.39) | NOTUMLIPGCNR2NPC1ALDH1A1 | |
| SCHEMBL31378007 | 0.77 | NOTUM (0.51) | NOTUMALDH1A1POLB | |
| SCHEMBL2850031 | 0.71 | MAPT (0.38) | NOTUMALDH1A1HTTPOLB | |
| SCHEMBL12827599 | 0.70 | GPR183 (0.46) | ALDH1A1HTTPOLB | |
| SCHEMBL26817417 | 0.69 | NOTUM (0.62) | NOTUMMAPK1NPC1ALDH1A1HTT | |
| SCHEMBL24729541 | 0.68 | PDE4B (0.39) | — | |
| SCHEMBL29801176 | 0.68 | PDE4B (0.39) | — | |
| SCHEMBL19926708 | 0.68 | ACHE (0.39) | ALDH1A1POLB | |
| Trifluoroacetic Acid SCHEMBL15664383 | 0.68 | DPP4 (0.38) | NOTUMLIPG | |
| SCHEMBL26130366 | 0.68 | BRD4 (0.48) | NOTUMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-B | HPK1 inhibitors and uses thereof | 锐格药业公司 | 2025-02-11 | — | — | CN | disclosed |