Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743615 | 0.83 | BCHE (0.42) | BCHENOTUMUSP2TSHRTDP1 | |
| SCHEMBL31378004 | 0.79 | NOTUM (0.54) | NOTUMUSP2MEN1KMT2AALDH1A1 | |
| SCHEMBL30196037 | 0.78 | KDM1A (0.53) | BCHENOTUM | |
| SCHEMBL20505758 | 0.78 | KDM1A (0.53) | BCHENOTUM | |
| SCHEMBL8127807 | 0.78 | BCHE (0.48) | BCHENOTUMUSP2TSHRTDP1 | |
| SCHEMBL13091978 | 0.77 | NOTUM (0.50) | BCHENOTUMOPRD1OPRK1 | |
| SCHEMBL8015593 | 0.77 | BCHE (0.47) | BCHENOTUMTSHRTDP1L3MBTL1 | |
| SCHEMBL8003261 | 0.74 | BCHE (0.47) | BCHENOTUMTSHRTDP1L3MBTL1 | |
| SCHEMBL1955620 | 0.73 | BCHE (0.55) | BCHENOTUMTSHRTDP1L3MBTL1 | |
| SCHEMBL5797625 | 0.71 | RAB9A (0.63) | BCHENOTUMTSHRL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-B | HPK1 inhibitors and uses thereof | 锐格药业公司 | 2025-02-11 | — | — | CN | disclosed |