Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127807 | 0.86 | BCHE (0.48) | BCHEKDM1ATSHRL3MBTL1TDP1 | |
| SCHEMBL6649116 | 0.81 | KDM1A (0.62) | BCHEKDM1ANOTUM | |
| SCHEMBL7154077 | 0.81 | KDM1A (0.62) | BCHEKDM1ANOTUM | |
| SCHEMBL13091978 | 0.76 | NOTUM (0.50) | BCHEOPRL1OPRD1OPRK1NOTUM | |
| SCHEMBL6653847 | 0.76 | KDM1A (0.45) | KDM1AOPRL1SMN1; SMN2LMNANOTUM | |
| SCHEMBL5797625 | 0.76 | RAB9A (0.63) | BCHETSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL31378010 | 0.74 | BCHE (0.48) | BCHETSHRL3MBTL1TDP1OPRD1 | |
| SCHEMBL6651006 | 0.73 | KDM1A (0.61) | BCHEKDM1ANOTUM | |
| SCHEMBL8014966 | 0.72 | BCHE (0.49) | BCHETSHRL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL30379140 | 0.72 | BCHE (0.49) | BCHETSHRL3MBTL1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121450-A | NON-STEROIDAL COMPOUNDS WHICH ARE HIGH AFFINITY, HIGH SELECTIVITY MODULATORS FOR STEROID RECEPTORS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0918774-A1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997049709-A1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-31 | — | — | WO | disclosed |