Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29554766 | 0.87 | NPC1 (0.71) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL2116912 | 0.87 | NPC1 (0.71) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL9526349 | 0.83 | NPC1 (0.66) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL299090 | 0.83 | NPC1 (0.66) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL8014966 | 0.83 | BCHE (0.49) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL27749835 | 0.82 | LMNA (0.45) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL27749593 | 0.82 | MEN1 (0.45) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL3662555 | 0.81 | NPC1 (0.60) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL27882103 | 0.81 | NPC1 (0.71) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM | |
| SCHEMBL8434185 | 0.80 | CNR2 (0.48) | RAB9ANPC1L3MBTL1ALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034480-A2 | SULFONAMIDE BICYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |