Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | HTR6 | P50406 | 6/20 | 0.43 |
| ▸ | HTR7 | P34969 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 5/20 | 0.43 |
| ▸ | HTR3A | P46098 | 5/20 | 0.43 |
| ▸ | HTR1D | P28221 | 4/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29243724 | 0.80 | ALDH1A1 (0.45) | HTR6HTR3AHTR2AADRB2HTR3E | |
| SCHEMBL31536997 | 0.80 | NCF1 (0.44) | CHRNB2CHRNA4HTR1AHTR6HTR7 | |
| SCHEMBL30047074 | 0.78 | HTR3A (0.55) | CHRNB2CHRNA4HTR1AHTR6HTR7 | |
| SCHEMBL24784244 | 0.78 | HTR3A (0.55) | CHRNB2CHRNA4HTR1AHTR6HTR7 | |
| Hydrochloric Acid SCHEMBL29974181 | 0.76 | HTR3A (0.54) | CHRNB2CHRNA4HTR1AHTR6HTR7 | |
| Hydrochloric Acid SCHEMBL21626121 | 0.76 | HTR3A (0.54) | CHRNB2CHRNA4HTR1AHTR6HTR7 | |
| Hydrochloric Acid SCHEMBL23403785 | 0.76 | HTR3A (0.54) | CHRNB2CHRNA4HTR1AHTR6HTR7 | |
| SCHEMBL24989544 | 0.76 | ALDH1A1 (0.47) | HTR1AHTR6HTR7HTR2BHTR3A | |
| SCHEMBL27307157 | 0.75 | PDE10A (0.39) | HTR1A | |
| SCHEMBL27307301 | 0.75 | DPP4 (0.38) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038395-A1 | BENZOPYRIDINONES AND BENZOPYRIMIDINONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2025-02-20 | — | — | WO | disclosed |