Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625344 | 0.72 | TNKS (1.00) | TNKSKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL31378592 | 0.71 | NPC1 (0.33) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL16625347 | 0.70 | TNKS (1.00) | TNKS | |
| SCHEMBL18918389 | 0.70 | TNKS (0.59) | TNKSKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL22201443 | 0.69 | ALDH1A1 (0.59) | TNKSKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL828493 | 0.68 | TNKS (0.63) | TNKSKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29639160 | 0.68 | TNKS (0.63) | TNKSKDM4ENPC1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL6648959 | 0.68 | ALDH1A1 (0.61) | TNKSKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL28924699 | 0.66 | TNKS (0.65) | TNKSKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL30161077 | 0.66 | TNKS (0.65) | TNKSKDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038395-A1 | BENZOPYRIDINONES AND BENZOPYRIMIDINONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2025-02-20 | — | — | WO | disclosed |